| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802547 | European Journal of Medicinal Chemistry | 2012 | 14 Pages |
Abstract
⺠A series of arylalkanol-piperidine derivatives (2a-y) were synthesized. ⺠Synthesized compounds were tested for triple reuptake inhibition and antidepressant activities. ⺠5 compounds exhibited high potency for 5-HT, NA and DA transporters. ⺠Some compounds showed antidepressant activities in TST and displayed desirable pharmacokinetic properties.
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Authors
Yong-Yong Zheng, Lin Guo, Xue-Chu Zhen, Jian-Qi Li,