| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802548 | European Journal of Medicinal Chemistry | 2012 | 7 Pages |
Abstract
⺠Very first report of toisomerase inhibitory activity of the friedelan derivatives. ⺠3D molecular docking on topoisomerase IIα (1 bgw, PDB). ⺠Prediction of nature of interactions of the drug molecules with enzyme. ⺠Helpful for drug designing and mechanism of drug resistance phenomena. ⺠Prediction of dose dependent inhibition activity against topoisomerase IIα.
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Authors
Amitava Mandal, Shilpi Ghosh, Ashim Kumar Bothra, Ashis Kumar Nanda, Pranab Ghosh,