Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802570 | European Journal of Medicinal Chemistry | 2012 | 14 Pages |
Abstract
⺠Conjugated derivatives of caudatin with cinnamic acids were synthesized. ⺠Most of the derivatives exhibited potent anti-HBV activity. ⺠The compound 18 exerted antivirus effects by interfering HBV promoters and enhancers. ⺠The mechanism of compound 18 is different from those of the nucleoside analogs.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Li-Jun Wang, Chang-An Geng, Yun-Bao Ma, Jie Luo, Xiao-Yan Huang, Hao Chen, Ning-Jia Zhou, Xue-Mei Zhang, Ji-Jun Chen,