| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802578 | European Journal of Medicinal Chemistry | 2012 | 10 Pages |
Abstract
⺠Retinoic acid was conjugated to octadecylamine. ⺠5-FU and retinoic acid conjugate were loaded in cholesterol NLCs. ⺠NLCs targeted LDL receptors of HT29 cells. ⺠IC50 of NLCs of retinoic acid conjugate and 5-FU was more than 5 fold of free 5-FU. ⺠NLCs of 5-FU and retinoic acid conjugate seems promising in colorectal cancer.
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Authors
Jaleh Varshosaz, Farshid Hassanzadeh, Hojjat Sadeghi, Sare Andalib,