| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802590 | European Journal of Medicinal Chemistry | 2012 | 10 Pages |
Abstract
⺠Seven-membered cyclometallated Pt(II) compounds as a new class of potential anticancer drugs. ⺠Non-planar arrangement of these compounds deduced from molecular structures. ⺠Remarkable antiproliferative activity in the human lung carcinoma, breast and colon cancer cell lines. ⺠These compounds modify the DNA tertiary structure, in a similar way than cisplatin.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Roldán Cortés, Margarita Crespo, Laia Davin, Raquel MartÃn, Josefina Quirante, Daniel Ruiz, Ramon Messeguer, Carme Calvis, Laura Baldomà , Josefa Badia, Mercè Font-BardÃa, Teresa Calvet, Marta Cascante,