Article ID Journal Published Year Pages File Type
7802603 European Journal of Medicinal Chemistry 2012 11 Pages PDF
Abstract
► 11 Chemists estimated synthetic accessibility of each other's lead-like molecules. ► Good agreement obtained between average chemist scores and SYLVIA software. ► Selection of compounds should be done by several chemists instead of individuals. ► Evaluation of synthetic accessibility for drugs since 1970. ► SYLVIA can be used efficiently to rank and prioritize virtual compound libraries.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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