Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802603 | European Journal of Medicinal Chemistry | 2012 | 11 Pages |
Abstract
⺠11 Chemists estimated synthetic accessibility of each other's lead-like molecules. ⺠Good agreement obtained between average chemist scores and SYLVIA software. ⺠Selection of compounds should be done by several chemists instead of individuals. ⺠Evaluation of synthetic accessibility for drugs since 1970. ⺠SYLVIA can be used efficiently to rank and prioritize virtual compound libraries.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Pascal Bonnet,