| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802604 | European Journal of Medicinal Chemistry | 2012 | 7 Pages |
Abstract
⺠A series of 5â²-deoxy-5-fluorocytidine derivatives synthesized in two-step process. ⺠We have characterized anti-cancer activity of 5â²-deoxy-5-fluorocytidine derivatives. ⺠Title compounds were non-mutagenic to Salmonella typhimurium tester strain. ⺠HeLa, NCI-69, PZ-HPV-7, MCF-7 cancer cell lines are highly sensitive to 5d, 5e. ⺠5d & 5e Showed potent antitumor activity compared to capecitabine in in vivo system.
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![Synthesis and biological activity evaluation of cytidine-5â²-deoxy-5-fluoro-N-[(alkoxy/aryloxy)] carbonyl-cyclic 2â²,3â²-carbonates](/preview/png/7802604.png "First Page Preview: Synthesis and biological activity evaluation of cytidine-5â²-deoxy-5-fluoro-N-[(alkoxy/aryloxy)] carbonyl-cyclic 2â²,3â²-carbonates")
Authors
V. Jhansi Rani, A. Raghavendra, P. Kishore, Y. Nanda Kumar, K. Hema Kumar, K. Jagadeeswarareddy,