Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802623 | European Journal of Medicinal Chemistry | 2012 | 8 Pages |
Abstract
⺠Seventeen 3-methanone-6-substituted-benzofuran derivatives were prepared. ⺠Seven of them have showed excellent antibacterial activities compared to the positive controls. ⺠The SAR studies confirmed that the hydroxyl group at C-6 position is essential to antibacterial activities. ⺠The functional groups at C-3 position plays important role in the antibacterial selectivity of these compounds.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jingbao Liu, Faqin Jiang, Xizhen Jiang, Wei Zhang, Jingjing Liu, Wenlu Liu, Lei Fu,