| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802631 | European Journal of Medicinal Chemistry | 2012 | 7 Pages |
Abstract
⺠New quinoline-5,8-dione and hydroxynaphthoquinone derivatives were synthesized. ⺠Tested for antiplasmodial activity against Plasmodium falciparum. ⺠Of the 15 compounds, 7a-c, 8a, 9b, 11, and 15 were effective in growth inhibition with an IC50 value below 5 μM. ⺠Compound 7a was most active with IC50 2.21 μM.
Related Topics
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Authors
Hidayat Hussain, Sabine Specht, Salem R. Sarite, Achim Hoerauf, Karsten Krohn,