Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802654 | European Journal of Medicinal Chemistry | 2011 | 17 Pages |
Abstract
⺠Thirty-six pyrazole derivatives were designed and synthesized. ⺠The active molecules induced apoptosis and caused aneuploid cells. ⺠The most active molecule 12d binds to a new target site on β-tubulin.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alessandro Balbi, Maria Anzaldi, Chiara Macciò, Cinzia Aiello, Mauro Mazzei, Rosaria Gangemi, Patrizio Castagnola, Mariangela Miele, Camillo Rosano, Maurizio Viale,