Article ID Journal Published Year Pages File Type
7802687 European Journal of Medicinal Chemistry 2011 8 Pages PDF
Abstract
► 29 imidazoisoindoles, imidazobenzimidazoles and isoindolinones synthesized. ► IC50 values against 3D7 Plasmodium falciparum ranged between 60 nM and >35 mM. ► 7 imidazoisoindoles assayed on mice infected with Plasmodium berghei. ► Up to 87% parasitemia inhibition on the 5th day, after 4 daily i.p. 25 mg/kg/day.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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