Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802751 | European Journal of Medicinal Chemistry | 2011 | 7 Pages |
Abstract
⺠Urease inhibitors have gained potential as novel drugs for the treatment of ulcer. ⺠We designed and synthesized a new series of Schiff based derivatives. ⺠They were most potent and low molecular weight inhibitors of the urease. ⺠Binding mode of Schiff base compounds was same for Jack bean and Helicobacter pylori urease.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Muhammad Adil S. Aslam, Shams-ul Mahmood, Mohammad Shahid, Aamer Saeed, Jamshed Iqbal,