| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802767 | European Journal of Medicinal Chemistry | 2011 | 11 Pages |
Abstract
⺠Arenesulfonylquinolones were synthesized and evaluated for antibacterial activity. ⺠Most compounds exhibited significant antibacterial activity. ⺠Antibacterial activity depends on the electronic effect of substituent groups. ⺠2D-QSAR models provide fine relationship linking structure and activity. âºDocking study of the most active 3b revealed similar binding mode to ciprofloxacin.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alaa A.-M. Abdel-Aziz, Yousif A. Asiri, Mohamed H.M. Al-Agamy,