| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802805 | European Journal of Medicinal Chemistry | 2011 | 9 Pages |
Abstract
⺠Forty five novel 2-arylamino-3-(arylsulfonyl)quinoxalines were synthesized. ⺠Most compounds exhibited potent in vitro cytotoxicities against tested cell lines. ⺠Compounds were tested as PI3Kα inhibitors. ⺠Compound 17 (PI3Kα IC50: 0.07 μM) showed the most potent cellular activities.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Peng Wu, Yi Su, Xiaowen Liu, Lei Zhang, Yong Ye, Jianchao Xu, Shaoyu Weng, Yani Li, Tao Liu, Shufang Huang, Bo Yang, Qiaojun He, Yongzhou Hu,