Article ID Journal Published Year Pages File Type
7802827 European Journal of Medicinal Chemistry 2011 5 Pages PDF
Abstract
► New triazolothiadiazines were obtained via ring closure reaction of triazol-3-thione. ► These compounds were tested were tested in vitro against various Candida species. ► The cytotoxicity of these derivatives was evaluated by MTT assay. ► Compound 2a was found to be the most potent derivative among these compounds. ► +π effect of substituents may have a considerable influence on anticandidal activity.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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