Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802827 | European Journal of Medicinal Chemistry | 2011 | 5 Pages |
Abstract
⺠New triazolothiadiazines were obtained via ring closure reaction of triazol-3-thione. ⺠These compounds were tested were tested in vitro against various Candida species. ⺠The cytotoxicity of these derivatives was evaluated by MTT assay. ⺠Compound 2a was found to be the most potent derivative among these compounds. âºÂ +Ï effect of substituents may have a considerable influence on anticandidal activity.
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Authors
Mehlika Dilek Altıntop, Zafer Asım Kaplancıklı, Gülhan Turan-Zitouni, Ahmet Ãzdemir, Gökalp İÅcan, GülÅen Akalın, Åafak Ulusoylar Yıldırım,