Article ID Journal Published Year Pages File Type
7802881 European Journal of Medicinal Chemistry 2011 11 Pages PDF
Abstract
► β-Tetrahydrocarbolinecarbonyldrazines were aromatized to β-carbolinecarbonyl- hydrazines. ► The aromatization decreased the proximity of the side chain to the carboline-cycle. ► The aromatization increased the in vitro anti-platelet aggregation activity. ► The aromatization increased the in vivo anti-thrombotic activity. ► These could be understood with a 3D QSAR analysis.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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