Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7802930 | European Journal of Medicinal Chemistry | 2011 | 8 Pages |
Abstract
⺠Thio-benzodiazepines were designed and synthesized. ⺠Most compounds showed good antitumor activity and binding affinity. ⺠We proposed a binding model for the thio-benzodiazepine-MDM2 complex.
Related Topics
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Authors
Chunlin Zhuang, Zhenyuan Miao, Lingjian Zhu, Yongqiang Zhang, Zizhao Guo, Jianzhong Yao, Guoqiang Dong, Shengzheng Wang, Yang Liu, Hai Chen, Chunquan Sheng, Wannian Zhang,