| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7802937 | European Journal of Medicinal Chemistry | 2011 | 6 Pages |
Abstract
⺠A series of 16 bispyridinium salts have been synthesized. ⺠Antitumor and inhibitory activities were tested against HT29 and ChoK respectively. âºÂ The higher antitumor activity was showed by compound 3a (IC50 = 0.84 μM). ⺠Compound 3g showed the higher inhibitory activity (IC50 = 0.3 μM). ⺠In both tests, the best results were obtained by derivatives bearing spacer p-biphenyl.
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Authors
Y. MartÃn-Cantalejo, B. Sáez, M.I. Monterde, M.T. Murillo, M.F. Braña,