Article ID Journal Published Year Pages File Type
7802976 European Journal of Medicinal Chemistry 2011 8 Pages PDF
Abstract
► A series of 4-aryl-1H-1,2,3-triazoles were evaluated as IDO inhibitors. ► Three compounds (1, 6, 8) possessed more IDO inhibitory potency than 1-MT. ► A small electron-withdrawing group near the triazole NH was required for inhibition.
Keywords
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Structure-activity relationship and enzyme kinetic studies on 4-aryl-1H-1,2,3-triazoles as indoleamine 2,3-dioxygenase (IDO) inhibitors
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