Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7803077 | European Journal of Medicinal Chemistry | 2011 | 9 Pages |
Abstract
⺠28 Novel 2,N6-disubstituted 1,2-dihydro-1,3,5-triazine-4,6-diamines prepared. ⺠Antimalarial activity against FCR-3 P. falciparum strain with IC50 = 0.99-49.75 μM. ⺠No red blood cell toxicity or haemolysis observed at 50 μM for any of the compounds.
Keywords
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Organic Chemistry
Authors
David Gravestock, Amanda L. Rousseau, Anna C.U. Lourens, Simon S. Moleele, Robyn L. van Zyl, Paul A. Steenkamp,