Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7803085 | European Journal of Medicinal Chemistry | 2011 | 11 Pages |
Abstract
⺠Synthesis of 30 new N-substituted-2-[(1E)-alkenyl]-4-(1H)-quinolones. ⺠MIC till 0.5 mg/L against one of the fast growing Mycobacteria in vitro. ⺠Substituents at N-1 influence the antimycobacterial activity. ⺠Best activity with 13-15 C-atoms overall in both side chains.
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Authors
Abraham A. Wube, Franz Bucar, Christina Hochfellner, Martina Blunder, Rudolf Bauer, Antje Hüfner,