| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7803086 | European Journal of Medicinal Chemistry | 2011 | 7 Pages |
Abstract
⺠D3CLP was more cytotoxic to K-562 than PBMCs. ⺠D3CLP induced a subdiploid population without changes in the cell cycle phases. ⺠The TUNEL results are consistent with an apoptotic cell death induction. ⺠Effector caspases activity increase in function of the time.
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![Antineoplastic activity of the thiazolo[5,4-b]quinoline derivative D3CLP in K-562 cells is mediated through effector caspases activation](/preview/png/7803086.png "First Page Preview: Antineoplastic activity of the thiazolo[5,4-b]quinoline derivative D3CLP in K-562 cells is mediated through effector caspases activation")
Authors
Ignacio González-Sánchez, José D. Solano, Marco A. Loza-MejÃa, Susana Olvera-Vázquez, Rogelio RodrÃguez-Sotres, Julio Morán, Alfonso Lira-Rocha, Marco A. Cerbón,