| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7803099 | European Journal of Medicinal Chemistry | 2011 | 12 Pages |
Abstract
⺠N-acylaminophenothiazines are a new family of multifunctional neuroprotective agents. ⺠Selective inhibition of BuChE vs. AChE. ⺠Good CNS penetration by PAMPA-BBB assay. ⺠Neuroprotection vs. oxidative stress, calcium overload, okadaic acid and beta-amyloid. ⺠Calcium channel modulating activity.
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Authors
Gema C. González-Muñoz, Mariana P. Arce, Beatriz López, Concepción Pérez, Alejandro Romero, Laura del Barrio, MarÃa Dolores MartÃn-de-Saavedra, Javier Egea, Rafael León, Mercedes Villarroya, Manuela G. López, Antonio G. GarcÃa, Santiago Conde,