Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7803108 | European Journal of Medicinal Chemistry | 2011 | 17 Pages |
Abstract
⺠A strategy was proposed for the development of organometallic antimalarial drugs. ⺠New series of substituted ferrocenylpyrrolo[1,2-a]quinoxalines were designed. ⺠Compounds were tested for their in vitro activity upon Plasmodium falciparum strains. ⺠Promising pharmacological results against FcB1, K1 and F32 strains were obtained.
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Authors
Jean Guillon, Elisabeth Mouray, Stéphane Moreau, Catherine Mullié, Isabelle Forfar, Vanessa Desplat, Solene Belisle-Fabre, Noël Pinaud, François Ravanello, Augustin Le-Naour, Jean-Michel Léger, Grace Gosmann, Christian Jarry, Gérard Déléris,