Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7803120 | European Journal of Medicinal Chemistry | 2011 | 5 Pages |
Abstract
⺠In this work we have synthesized two new series of bis-pyrazolines derivatives. ⺠Bis-pyrazolines compounds are obtained by microwave-assisted reaction. ⺠This synthesis allowed the formation of the desired compounds in excellent yields. ⺠Biological assays show that two compounds are active in several tumor cell lines. ⺠These compounds exhibited promising activities in accord whit GI50 and LC50 values.
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Authors
Braulio Insuasty, Angélica GarcÃa, Jairo Quiroga, Rodrigo Abonia, Alejandro Ortiz, Manuel Nogueras, Justo Cobo,