Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7803179 | European Journal of Medicinal Chemistry | 2011 | 7 Pages |
Abstract
⺠A new series of 4-hetarylpyrazoles and furo[2,3-c]pyrazoles were synthesized. ⺠The antimicrobial activity of new compounds have been screened. ⺠Compound 12 showed equipotent activity with chloramphenicol against B. subtilis (MIC 3.125 μg/mL). ⺠Compounds 7 and 13 were found to exhibit the most potent in vitro antifungal activity. ⺠The attachment of furyl moiety to pyrazole ring is crucial in developing a new antimicrobial agent.
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Organic Chemistry
Authors
Samir Bondock, Wesam Khalifa, Ahmed A. Fadda,