| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7803192 | European Journal of Medicinal Chemistry | 2011 | 7 Pages |
Abstract
⺠Thienopyrimidines are novel and potent class of protein kinase CK2 inhibitors. ⺠Thienopyrimidines display selectivity towards CK2 and ATP-competitive type of inhibition. ⺠Key role in the structure of thienopyrimidine CK2 inhibitors plays carboxyl group.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2](/preview/png/7803192.png "First Page Preview: Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2")
Authors
Andriy G. Golub, Volodymyr G. Bdzhola, Nadiia V. Briukhovetska, Anatoliy O. Balanda, Olexander P. Kukharenko, Igor M. Kotey, Olga V. Ostrynska, Sergiy M. Yarmoluk,