Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7803202 | European Journal of Medicinal Chemistry | 2011 | 13 Pages |
Abstract
⺠Fourteen prenylated flavonoids were synthesized, twelve of them for the first time. ⺠Compounds 6, 15, 16 clearly demonstrated the best results in cell growth inhibition. ⺠Compounds 3 and 6 caused the highest increases in the % of cells in G1 phase. ⺠Compound 6 revealed a significant increase in the levels of apoptosis.
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Authors
Marta Perro Neves, Honorina Cidade, Madalena Pinto, Artur M.S. Silva, LuÃs Gales, Ana Margarida Damas, Raquel T. Lima, M. Helena Vasconcelos, Maria de São José Nascimento,