| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7803247 | European Journal of Medicinal Chemistry | 2011 | 7 Pages |
Abstract
⺠3-Methylene-substituted indolinone scaffold as antimalarials. ⺠Reaction is highly regioselective leading to the preferred formation of the Z isomer. ⺠3-methylene-substituted indolinones as inhibitors of falcipain-2. ⺠3-methylene-substituted indolinones displayed antiplasmodial activity in low micromolar range.
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Authors
S. Praveen Kumar, Jiri Gut, Rita C. Guedes, Philip J. Rosenthal, Maria M.M. Santos, Rui Moreira,