| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7803251 | European Journal of Medicinal Chemistry | 2011 | 7 Pages |
Abstract
⺠Leishmaniasis is a tropical complex infection caused by the genus Leishmania. ⺠Most drugs currently in use are toxic, expensive and require long-term treatment. ⺠Novel 5-(5-nitro-2-furyl)-1,3,4-thiadiazoles as antileishmanial agents are reported. ⺠Piperazin-linked benzamidine derivatives were found very active. ⺠Substitution on amidine nitrogen had profound role in antileishmanial activity.
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Authors
Azar Tahghighi, Farzane Rezazade Marznaki, Farzad Kobarfard, Siavoush Dastmalchi, Javid Shahbazi Mojarrad, Sepideh Razmi, Sussan Kabudanian Ardestani, Saeed Emami, Abbas Shafiee, Alireza Foroumadi,