| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7803300 | European Journal of Medicinal Chemistry | 2011 | 10 Pages |
Abstract
A series of quinoline derivatives have been designed, synthesized and evaluated in vitro for their cholinesterase inhibitory activity and selectivity and Ca channel antagonist. Docking analysis allowed to identify the binding mode in the active site and to explain the observed selectivities.
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Isabelle Tomassoli, Lhassane Ismaili, Marc Pudlo, Cristóbal de los RÃos, Elena Soriano, Inés Colmena, Luis GandÃa, Luis Rivas, Abdelouahid Samadi, José Marco-Contelles, Bernard Refouvelet,