Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7803305 | European Journal of Medicinal Chemistry | 2011 | 6 Pages |
Abstract
âºA hit-to-lead optimization was conducted based on a novel M2 inhibitor. âºA structure-activity relationship by modifying the pinane scaffold was listed in the paper. âºCompound 8e was identified to be a highly potent agent against wild-type influenza A virus which is nearly 240-fold more active than amantadine.
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Authors
Xin Zhao, Chufang Li, Shaogao Zeng, Wenhui Hu,