Article ID Journal Published Year Pages File Type
7803305 European Journal of Medicinal Chemistry 2011 6 Pages PDF
Abstract
►A hit-to-lead optimization was conducted based on a novel M2 inhibitor. ►A structure-activity relationship by modifying the pinane scaffold was listed in the paper. ►Compound 8e was identified to be a highly potent agent against wild-type influenza A virus which is nearly 240-fold more active than amantadine.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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