Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7803310 | European Journal of Medicinal Chemistry | 2011 | 6 Pages |
Abstract
⺠Replacement of the trimethoxyphenyl ring of phenstatin with a trimethoxyindole moiety. ⺠The 2-aroylindoles were synthesized via a palladium-catalyzed domino reaction. ⺠Compounds showed moderate cytotoxic and antitubulin activities. ⺠The 4,5,6-trimethoxy substitution pattern is an appropriate structural feature.
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Authors
Martin Arthuis, Renée Pontikis, Guy G. Chabot, Lionel Quentin, Daniel Scherman, Jean-Claude Florent,