Article ID Journal Published Year Pages File Type
7803312 European Journal of Medicinal Chemistry 2011 16 Pages PDF
Abstract
►This work aim to synthesize a novel compounds with activity against both HIV & TB which are normally exist as co-infection. ►Some of the compounds active against dormant Mycobacterium tuberculosis for that no specific drugs are available. ►Compound B21 displayed promising activity against the replication of HIV-1 cells (EC50 1.69 μM). ►B21 inhibit both HIV and MTB.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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