Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7803337 | European Journal of Medicinal Chemistry | 2011 | 14 Pages |
Abstract
⺠New quinoxalines derivatives have been synthesized to evaluate their cancer chemopreventive activity. ⺠The inhibitory effects of compounds 1-21 on Epsteine Barr virus early antigen (EBV-EA) activation induced by TPA have been studied. ⺠The in vivo two-stage carcinogenesis test of compound 12 was studied. ⺠The synthesized compounds docked into c-kit protein-tyrosine kinase.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shadia A. Galal, Ahmed S. Abdelsamie, Harukuni Tokuda, Nobutaka Suzuki, Akira Lida, Mahmoud M. ElHefnawi, Raghda A. Ramadan, Mona H.E. Atta, Hoda I. El Diwani,