| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7803346 | European Journal of Medicinal Chemistry | 2011 | 12 Pages |
Abstract
⺠β-Lapachone derivatives were obtained with antitumor activity. ⺠β-Lapachone-based 1,2,3-triazoles inducing apoptotic cell death mediated by ROS generation. ⺠β-Lapachone-based 1,2,3-triazoles can be considered prototypes for cancer therapy.
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Authors
Eufrânio N. Jr., Bruno C. Cavalcanti, Tiago T. Guimarães, Maria do Carmo F.R. Pinto, Igor O. Cabral, Cláudia Pessoa, LetÃcia V. Costa-Lotufo, Manoel O. de Moraes, Carlos K.Z. de Andrade, Marcelo R. dos Santos, Carlos A. de Simone,