| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7803350 | European Journal of Medicinal Chemistry | 2011 | 4 Pages |
Abstract
⺠A novel series of ureas derivatives had designed and synthesized. ⺠Some of the prepared compounds showed potential cytotoxicity against several human cancer cell lines. And some compounds displayed more or similar potent cytotoxic activities against cancer cell lines in comparison with 5-FU. ⺠However, most of the compounds showed weak cytotoxicity against MCF-7 cancer cell line. The target or mechanism for this class of compounds might be different from reported urea derivatives.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chuanfei Jin, Yong-Ju Liang, Hongwu He, Liwu Fu,