Article ID Journal Published Year Pages File Type
7827975 Tetrahedron 2018 7 Pages PDF
Abstract
DIPEA-promoted one-pot synthesis of perfluoroalkylated indolizinylphosphonates by the reaction of pyridines 1, bromomethyl ketones 2 with perfluoproalkynylphosphonates 3 is described. This procedure is compatible with a broad range of functional groups in both pyridines and ketones with good yields. The reaction proceeds through a tandem CN bond formation followed by an intramolecular cyclization.90
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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