Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7827975 | Tetrahedron | 2018 | 7 Pages |
Abstract
DIPEA-promoted one-pot synthesis of perfluoroalkylated indolizinylphosphonates by the reaction of pyridines 1, bromomethyl ketones 2 with perfluoproalkynylphosphonates 3 is described. This procedure is compatible with a broad range of functional groups in both pyridines and ketones with good yields. The reaction proceeds through a tandem CN bond formation followed by an intramolecular cyclization.90
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Authors
Hao Liu, Dong He, Zhenhua Sun, Weimin He, Jing Han, Jie Chen, Hongmei Deng, Min Shao, Hui Zhang, Weiguo Cao,