Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7841834 | Journal of Molecular Liquids | 2018 | 23 Pages |
Abstract
In this work, the suitability of the PDEAEMA-based nanogels to be used as anticancer nanocarriers is analyzed. Nanogels show high drug loading and encapsulation efficiency together with pH-dependent drug delivery. The uptake of DOXO-loaded nanogels into cancer cells and the subsequent progressive release of the drug from the nanogels into the cytoplasm and diffusing to the cell nuclei are demonstrated.62
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Aintzane Pikabea, Eva Villar-Álvarez, Jacqueline Forcada, Pablo Taboada,