A novel approach for the simultaneous extraction of dihydroquercetin and arabinogalactan from Larix gmelinii by homogenate-ultrasound-synergistic technique using the ionic liquid

An ionic liquid-based homogenate-ultrasound-synergistic technique was proposed to simultaneously extract dihydroquercetin and arabinogalactan from Larix gmelinii stumps. The appropriate extraction solvent of [C2mim]Br was screened from thirteen kinds of imidazolium-based ionic liquids. The optimal conditions for the proposed method obtained by response surface methodology were a [C2mim]Br concentration of 0.87 mol/L, IL-HUSE time of 24 min, liquid/solid ratio of 14 mL/g, and ultrasound power of 240 W. Under these conditions, the satisfied extraction yields were 53.09 ± 2.24 mg/g for dihydroquercetin and 152.48 ± 5.78 mg/g for larch arabinogalactan. Validation studies suggested that the improved method was capable of extraction of dihydroquercetin and arabinogalactan from L. gmelinii stumps. High extraction yields of dihydroquercetin and arabinogalactan obtained from the recycled [C2mim]Br indicated that the proposed method is a highly efficient technique. The present research indicates that the improved process shows promising prospects for application to the preparation of bioactive substances from plant materials.