Surface tension mediation by Na-based ionic polarization and acidic fragmentation: Inference of hypertension

Overdosing of Na(Cl, C5H8NO4) can raise one's blood pressure but moderately intaking of C6H8O6 ascorbic and C2H4O2 acetic acids effects contrastingly with mechanisms yet to be clear. From the perspective of hydrogen bond (O:HO or HB with “:” being electron lone pairs of oxygen) cooperativity, we show phonon-spectrometrically that solvation of the Na-based doses raises their solution surface tension by ionic polarization, but solvation of the organic acids performs contrastingly by dipolar fragilization. The Na-based doses dissolve into Na+ cations and anions that serve each as a charge center to cluster, stretch, and polarize the solvent O:HO bonds, raising the viscosity of the solution. However, the acidic dipoles break the solvation network into small fragments, helping to the blood flowing. Findings could offer workable mechanisms for hypertension medication and prevention.