Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7843477 | Journal of Molecular Liquids | 2018 | 8 Pages |
Abstract
The objective of this research work was to measure the solubility of mycophenolate mofetil (MPM) in ten different pure solvents at temperatures T = 298.2 K to 318.2 K and pressure p = 0.1 MPa. The solubilities of MPM in mole fraction were obtained maximum in ethyl acetate (9.28 Ã 10â 2) and minimum in water (4.16 Ã 10â 6) at “T = 318.2 K” and similar trends were also observed at each temperature investigated. Higher solute-solvents molecular interactions were observed in MPM-ethyl acetate and MPM-Transcutol. Apparent thermodynamic analysis indicated an endothermic and entropy-driven dissolution of MPM in each solvent investigated.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Mohd Abul Kalam, Abdul Arif Khan, Aws Alshamsan, Anzarul Haque, Faiyaz Shakeel,