| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7860772 | Journal of Controlled Release | 2018 | 22 Pages |
Abstract
Model of CP-Dox's enhancement of the host antitumor immune response in 4T1 mammary carcinoma. CP-Dox treatment generates inflammatory chemokines and IFN-γ. Chemokine production leads to the recruitment of leukocytes including CD8 + T cells and inflammatory monocytes. CD8 + T cells, in the presence of increased IFN-γ, contribute to controlling the primary tumor and preventing metastasis.158
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Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
Eric M. Mastria, Leon Y. Cai, Matthew J. Kan, Xinghai Li, Jeffrey L. Schaal, Steven Fiering, Michael D. Gunn, Mark W. Dewhirst, Smita K. Nair, Ashutosh Chilkoti,