| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7860987 | Journal of Controlled Release | 2017 | 9 Pages |
Abstract
A bio-inspired, self-adherent microneedle (MN) patch is designed for effective transdermal protein drug delivery. The dual-functional MN patch achieved not only a firm adhesion to live animal skin tissue, but also a prolonged insulin drug delivery following a mild loading process into swellable tips with minimal loss of biofunctionality. This transdermal delivery platform using self-adherent MN patches can be applied for a variety of protein drugs requiring sustained release kinetics.247
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
Keum-Yong Seong, Min-Soo Seo, Dae Youn Hwang, Eoin D. O'Cearbhaill, Seamus Sreenan, Jeffrey M. Karp, Seung Yun Yang,