Optimizing novel implant formulations for the prolonged release of biopharmaceuticals using in vitro and in vivo imaging techniques

Article ID	Journal	Published Year	Pages	File Type
7861668	Journal of Controlled Release	2016	40 Pages	PDF

Keywords

SDS SEC NIR mRNA ROI GAPDH PAGE FCS s.c.DOL PBS ISG DLS Stat1 Sustained release RNA ribonucleic acid polyacrylamide gel electrophoresis standard deviation Implant Tem interferon IFN interferon stimulated gene Interferon-β Freeze-Drying PCs messenger ribonucleic acid subcutaneous sodium dodecyl sulfate fetal calf serum Intramuscular Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)Phosphate buffered saline signal transducer and activator of transcription 1 Methylcellulose SEM Lane i.m.region of interest Multiple sclerosis Scanning electron microscopy Transmission electron microscopy Near-infrared IVIVC Hyaluronan polymerase chain reaction Dynamic Light Scattering polyethylene glycol PEG Size exclusion chromatography glyceraldehyde 3-phosphate dehydrogenase

Related Topics

Physical Sciences and Engineering Materials Science Biomaterials

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Optimizing novel implant formulations for the prolonged release of biopharmaceuticals using in vitro and in vivo imaging techniques

Authors

Susanne Beyer, Li Xie, Mike Schmidt, Natasja de Bruin, Mukul Ashtikar, Sabrina Rüschenbaum, Christian M. Lange, Vitali Vogel, Werner Mäntele, Michael J. Parnham, Matthias G. Wacker,