| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7862096 | Journal of Controlled Release | 2016 | 53 Pages |
Abstract
This work investigates the macro and micro structural material properties of dissolvable microprojections for vaccine delivery, containing common stabilizing sugars and polyols. This uses a range of techniques (microscopy, nanoindentation, synchrotron FT-FIR) to measure material modulus, projection strength, projection amorphous/crystalline structure, as well skin penetration, dissolution and diffusion. This uniquely shows the impact of pharmaceutical stabilisers on microdevice manufacture/function.104
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
Anthony P. Raphael, Michael L. Crichton, Robert J. Falconer, Stefano Meliga, Xianfeng Chen, Germain J.P. Fernando, Han Huang, Mark A.F. Kendall,