Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7863250 | Journal of Controlled Release | 2015 | 29 Pages |
Abstract
The hydrophobically associated multiple monocomplex (HMplex) composed of siRNA, BZT and Pluronic F-68 was developed for siRNA/drug co-delivery. Bcl-2 targeting HMplexes enhanced significantly both mRNA down-regulation by siRNA and apoptosis induction by BZT, leading to efficient tumor suppression.81
Keywords
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
Eunjung Lee, Changhwoa Oh, In-San Kim, Ick Chan Kwon, Sehoon Kim,