Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7866118 | Materials Science and Engineering: C | 2018 | 15 Pages |
Abstract
The present work aimed to study the properties of a novel nanocomposite with promising biomedical applications. Nanocomposites were prepared by the addition of different concentrations of chitosan decorated carbon nanotubes to acrylamide-co-acrylic acid hydrogels. The nanocomposites chemical structure was characterized by Fourier Transform Infrared Spectroscopy (FT-IR). The FT-IR shows the typical bands due to the hydrogel and additionally the peaks at 1750â¯cmâ1 and 1450â¯cmâ1 that correspond to the carbon nanotubes incorporated into the polymer matrix. Mechanical properties and swelling measurements in different buffer solutions were also performed. The nanocomposites showed improved mechanical properties and a stronger pH-response. In order to evaluate antimicrobial activity, the growth and adhesion of Staphylococcus aureus to nanocomposites were studied. Cytocompatibility was also evaluated by MTT assay on MDCK and 3T3 cell lines. The nanocomposites were found to be cytocompatible and showed a reduced bacterial colonization.
Keywords
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
Romina Bellingeri, Lucinda Mulko, Maria Molina, Natalia Picco, Fabrisio Alustiza, Carolina Grosso, Adriana Vivas, Diego F. Acevedo, Cesar A. Barbero,