Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7866830 | Materials Science and Engineering: C | 2016 | 7 Pages |
Abstract
Electrochemically assisted deposition was utilized to produce ceramic coatings on the basis of magnesium ammonium phosphate (struvite) on corundum-blasted titanium surfaces. By the addition of defined concentrations of strontium nitrate to the coating electrolyte Sr2Â + ions were successfully incorporated into the struvite matrix. By variation of deposition parameters it was possible to fabricate coatings with different kinetics of Sr2Â + into physiological media, whereas the release of therapeutically relevant strontium doses could be sustained over several weeks. Morphological and crystallographic examinations of the immersed coatings revealed that the degradation of struvite and the release of Sr2Â + ions were accompanied by a transformation of the coating to a calcium phosphate based phase similar to low-crystalline hydroxyapatite. These findings showed that strontium doped struvite coatings may provide a promising degradable coating system for the local application of strontium or other biologically active metal ions in the implant-bone interface.
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Authors
M. Meininger, C. Wolf-Brandstetter, J. Zerweck, F. Wenninger, U. Gbureck, J. Groll, C. Moseke,