| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7868603 | Materials Science and Engineering: C | 2016 | 38 Pages |
Abstract
We next produced fluorescent, biocompatible, aptamer-conjugated GNRs by performing ligand exchange followed by bioconjugation to anti-cancer oligonucleotide AS1411. In vitro studies showed that our nanoconstructs selectively target cancer cells while showing negligible cytotoxicity. As a result, our aptamer-conjugated GNRs constitute ideal cancer-selective multifunctional probes and promising candidates as photothermal therapy agents.
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Authors
Maria Elena Gallina, Yu Zhou, Christopher J. Johnson, David Harris-Birtill, Mohan Singh, Hailin Zhao, Daqing Ma, Tony Cass, Daniel S. Elson,